Martin Rentzsch was trained at the Folkwang University of the Arts in Essen. A first engagement took him to the Thalia Theater Hamburg, where he worked with directors such as Karin Henkel and Jürgen Flimm. From 2000 he was permanently engaged at the Schauspielhaus Bochum, where he created works with Elmar Goerden and Wilfried Minks. In 2008 he was awarded the Bochum Theater Prize. Since the 2009/10 season Martin Rentzsch has been a member of the ensemble of Schauspiel Frankfurt and has been part of the Berliner Ensemble since the 2017/18 season.